Placenta

Expression of PAPPA2 in human fetomaternal interface and involvement in trophoblast invasion and migration

H. Y. Wang, Zhang, Z., Yu, S., Wang, H. Y., Zhang, Z., and Yu, S., Expression of PAPPA2 in human fetomaternal interface and involvement in trophoblast invasion and migration, vol. 15, p. -, 2016.

Pregnancy-associated plasma protein-A 2 (PAPPA2) is a placental-enriched gene that is important for normal human placentation and defects in the gene can cause complications in pregnancy. Yet the exact expression pattern and role of PAPPA2 in the human fetomaternal interface are not clear. In this study, in situ hybridization (ISH) and immunohistochemistry (IHC) were employed to examine the spatial and temporal expression of PAPPA2 in the human fetomaternal interface.

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