PIK3CA

Study of PIK3CA, BRAF, and KRAS mutations in breast carcinomas among Chinese women in Qinghai

Y. L. Wang, Dai, X., Li, Y. D., Cheng, R. X., Deng, B., Geng, X. X., and Zhang, H. J., Study of PIK3CA, BRAF, and KRAS mutations in breast carcinomas among Chinese women in Qinghai, vol. 14, pp. 14840-14846, 2015.

Phosphatidylinositol-3-OH kinase and RAS-activated signaling pathways play an important role in tumor formation. Abnormalities in relevant genes play essential roles in the occurrence and development of many human cancers. Studies of breast cancer have mainly focused on the women in western countries, but few studies have examined the frequency of mutations in PIK3CA, BRAF, and KRAS in Chinese breast cancer patients.

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