Personalized medicine

Pharmacogenomics: accessing important alleles by imputation from commercial genome-wide SNP arrays

R. Liboredo and Pena, S. D. J., Pharmacogenomics: accessing important alleles by imputation from commercial genome-wide SNP arrays, vol. 13, pp. 5713-5721, 2014.

Personalized medicine is becoming a medical reality, as important genotype-phenotype relationships are being unraveled. The availability of pharmacogenomic data is a key element of individualized care. In this study, we explored genotype imputation as a means to infer important pharmacogenomic alleles from a regular commercially available genome-wide SNP array. Using these arrays as a starting point can reduce testing costs, increasing access to these pharmacogenomic data and still retain a larger amount of genome-wide information.

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