Penta D allele

Analysis of an “off-ladder” allele at the Penta D short tandem repeat locus

Y. L. Yang, Wang, J. G., Wang, D. X., Zhang, W. Y., Liu, X. J., Cao, J., and Yang, S. L., Analysis of an “off-ladder” allele at the Penta D short tandem repeat locus, vol. 14, pp. 15096-15101, 2015.

Kinship testing of a father and his son from Guangxi, China, the location of the Zhuang minority people, was performed using the PowerPlex® 18D System with a short tandem repeat typing kit. The results indicated that both the father and his son had an off-ladder allele at the Penta D locus, with a genetic size larger than that of the maximal standard allelic ladder. To further identify this locus, monogenic amplification, gene cloning, and genetic sequencing were performed.

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