Pathology

Pathology of the lower nasolacrimal duct mucosa at multiple time points after lacrimal retrograde catheterization in rabbit

L. Ye, Peng, Y., Wang, Y., Zeng, K., and Zhang, J. X., Pathology of the lower nasolacrimal duct mucosa at multiple time points after lacrimal retrograde catheterization in rabbit, vol. 14, pp. 7929-7936, 2015.

Lacrimal duct obstruction is a common eye disease, and obstruction of the nasolacrimal duct accounts for over 50% of these cases. Nasolacrimal duct obstruction is usually treated surgically. Lacrimal retrograde catheterization is a novel surgical approach with a high success rate and a relatively high recurrence rate. In this study, we examined the postoperative pathological changes in the lower nasolacrimal duct mucosa at multiple time points (2, 4, 6, 8, 10, 12, and 14 weeks) after retrograde lacrimal dilated drainage tube implantation in rabbits.

Effect of age on the immune system and pathology of mice with chronic graft-versus-host disease lupus nephritis

X. F. Ma, Xu, F. L., Gao, L. F., Wang, Y. X., and Pan, Z. B., Effect of age on the immune system and pathology of mice with chronic graft-versus-host disease lupus nephritis, vol. 14, pp. 10999-11005, 2015.

We investigated the effect of age on the expression of immune molecules [ANA, C4, double stranded DNA (dsDNA), CD16/32, CD19, CD3, and CD64], urine protein, and pathology in mice with chronic graft-versus-host disease (cGVHD) lupus nephritis (LN), and their relationship with reactivity index score. Mouse models of cGVHD LN were established, and mice were randomly divided into four aged-based groups of nine mice each. Serum levels of ANA, C4, and dsDNA were determined, the urine protein levels were assessed, and expression levels of CD16/32, CD19, CD3, and CD64 were measured.

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