Pancreatic adenocarcinoma

Integrated microRNA-mRNA analysis of pancreatic ductal adenocarcinoma

P. F. Liu, Jiang, W. H., Han, Y. T., He, L. F., Zhang, H. L., and Ren, H., Integrated microRNA-mRNA analysis of pancreatic ductal adenocarcinoma, vol. 14, pp. 10288-10297, 2015.

The main aim of this study was to explore the underlying molecular mechanisms and potential target molecules of pancreatic adenocarcinoma. The miRNA (GSE32678) and mRNA (GSE32676) expression profiles of patients with pancreatic ductal adenocarcinoma and healthy controls were downloaded from the Gene Expression Omnibus database. Differentially expressed miRNA and differentially expressed genes were identified by analyzing the microarray algorithm after data preprocessing. Functional analysis was conducted by the Database for Annotation, Visualization and Integrated Analysis.

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