High levels of glucose promote the activation of hepatic stellate cells via the p38-mitogen-activated protein kinase signal pathway
“High levels of glucose promote the activation of hepatic stellate cells via the p38-mitogen-activated protein kinase signal pathway”, vol. 15, p. -, 2016.
, The relationship between the p38-mitogen-activated protein kinase (p38-MAPK) signal pathway and high glucose-induced hepatic stellate cell (HSC) activation was investigated in this study. Sixty human HSC samples were randomly selected and used in the control (cultured normally), high-glucose (cultured in the presence of high glucose), and blocking (cultured under high-glucose conditions in the presence of the p38-MAPK inhibitor, SB203580) groups.