p38 MAPK

Effect of curcumin on p38MAPK expression in DSS-induced murine ulcerative colitis

C. - P. Li, Li, J. - H., He, S. - Y., Chen, O., and Shi, L., Effect of curcumin on p38MAPK expression in DSS-induced murine ulcerative colitis, vol. 14, pp. 3450-3458, 2015.

The aim of this study was to determine the therapeutic effect of curcumin on dextran sulfate sodium-induced ulcerative colitis (UC) and to explore the related mechanism. Sixty mice were randomly divided into 6 groups. A group was the normal control group; B group was the model group; C group was the 1.5 mg/kg dexamethasone group based on the B group; and D, E and F groups were 15, 30, and 60 mg/kg curcumin groups, respectively, based on the B group.

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