Ovary

Temporal and spatial expression profiles of Frizzled 3 in the ovary during the estrous cycle

S. B. Wang, Liu, Y. P., Zhang, Z. H., Wang, Z. K., Xu, Y. X., Wang, Z. C., Wang, S. B., Liu, Y. P., Zhang, Z. H., Wang, Z. K., Xu, Y. X., Wang, Z. C., Wang, S. B., Liu, Y. P., Zhang, Z. H., Wang, Z. K., Xu, Y. X., and Wang, Z. C., Temporal and spatial expression profiles of Frizzled 3 in the ovary during the estrous cycle, vol. 15, p. -, 2016.

Frizzled 3 is an important receptor in the Wnt/β-catenin pathway, a conserved signaling pathway that regulates gene expression and controls diverse developmental processes. However, the role of this protein during follicular development in the adult ovary is not known. The present study was designed to investigate the expression and localization of Frizzled 3 mRNA and protein during the estrous cycle in the mouse ovary through in situ hybridization (ISH), real-time quantitative polymerase chain reaction, immunohistochemistry and western blot.

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