Opg/Rankl mRNA dynamic expression in the bone tissue of ovariectomized rats with osteoporosis
“Opg/Rankl mRNA dynamic expression in the bone tissue of ovariectomized rats with osteoporosis”, vol. 14, pp. 9215-9224, 2015.
, We established animal models of osteoporosis in ovariectomized rats to detect osteoprogerin (Opg)/receptor activator of nuclear factor-κB ligand (Rankl) mRNA expression levels in the tibias and serum estradiol concentrations at different time points. Sixty Sprague-Dawley female rats were randomly selected and divided into an ovariectomized (OVX) group and sham-operated (SHAM) group. In the SHAM group, only a small amount of abdominal fat and tissues was removed from the rats.