Ovariectomized rats

Opg/Rankl mRNA dynamic expression in the bone tissue of ovariectomized rats with osteoporosis

C. W. Li, Liang, B., Shi, X. L., and Wang, H., Opg/Rankl mRNA dynamic expression in the bone tissue of ovariectomized rats with osteoporosis, vol. 14, pp. 9215-9224, 2015.

We established animal models of osteoporosis in ovari­ectomized rats to detect osteoprogerin (Opg)/receptor activator of nuclear factor-κB ligand (Rankl) mRNA expression levels in the tib­ias and serum estradiol concentrations at different time points. Sixty Sprague-Dawley female rats were randomly selected and divided into an ovariectomized (OVX) group and sham-operated (SHAM) group. In the SHAM group, only a small amount of abdominal fat and tissues was removed from the rats.

Subscribe to Ovariectomized rats