Ovarian cancer

Effects of the balance between type 1 and type 2 T helper cells on ovarian cancer

C. J. Hao, Li, J., Liu, P., Li, X. L., Hu, Y. Q., Sun, J. C., Wei, Y., Hao, C. J., Li, J., Liu, P., Li, X. L., Hu, Y. Q., Sun, J. C., and Wei, Y., Effects of the balance between type 1 and type 2 T helper cells on ovarian cancer, vol. 15, p. -, 2016.

The balance between type 1 and type 2 T helper cells (the Th1-Th2 balance) is closely correlated with cancer, but the correlation in ovarian cancer remains unconfirmed. We investigated the Th1-Th2 balance for the diagnosis, treatment, and prognostic evaluation of ovarian cancer. Fifty healthy subjects and 50 ovarian cancer patients were recruited. The levels of various cytokines were determined in sera and ovarian cancer tissues using a Th1-Th2 human cytokine array.

Correlations between the COMT gene rs4680 polymorphism and susceptibility to ovarian cancer

W. Pan and Liao, H., Correlations between the COMT gene rs4680 polymorphism and susceptibility to ovarian cancer, vol. 14, pp. 16813-16818, 2015.

The objective of this study was to perform a systematic review of the correlations between the single nucleotide polymorphism rs4680 in the catechol-O-methyltransferase (COMT) gene and susceptibility to ovarian cancer. A computer search was carried out for relevant case-control studies published between January 2000 to January 2014 in databases such as Ovid, EBSCO, PubMed, CNKI, CBMDISC, VIP, and WanFang Data. The literature was screened based on inclusion and exclusion criteria.

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