Ovarian cancer

MTHFR A1298C polymorphism and ovarian cancer risk: a meta-analysis

X. Y. Shi and Shen, Q., MTHFR A1298C polymorphism and ovarian cancer risk: a meta-analysis, vol. 14, pp. 8211-8218, 2015.

Numerous studies have evaluated the association between the MTHFR A1298C polymorphism and ovarian cancer risk. However, the specific association is still controversial. Therefore, we performed the present meta-analysis. A systematic literature search of PubMed and Embase databases was undertaken in August 2014, and the reference lists of articles were retrieved. ORs with their 95%CI were calculated to evaluate the strength of the association. Meta-analysis was performed using the STATA version 12.0 software package and publication bias was investigated by Begg’s funnel plot.

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