Ovarian cancer

Association of the genetic polymorphisms of NFKB1 with susceptibility to ovarian cancer

L. P. Chen, Cai, P. S., and Liang, H. B., Association of the genetic polymorphisms of NFKB1 with susceptibility to ovarian cancer, vol. 14, pp. 8273-8282, 2015.

Nuclear factor-κB (NF-κB), a transcription factor that is activated by various stimuli, is associated with the pathogenesis of several cancers. One functional polymorphism, -94 insertion/deletion ATTG (rs28362491), in the human NFKB1 gene (one member of the NF-κB gene family) is associated with increased risk of various cancers. However, only one study has reported that rs28362491 is significantly associated with ovarian cancer.

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