Osteoarthritis

Effect of high-intensity exercise on interleukin-15 expression in rabbit synovia

Y. H. Wang, Li, X. D., Zhu, W. B., and Sun, G. F., Effect of high-intensity exercise on interleukin-15 expression in rabbit synovia, vol. 14, pp. 13852-13859, 2015.

The objective of this study was to examine the effect of high-intensity exercise on interleukin-15 (IL-15) expression in rabbit synovia. We utilized 24 New Zealand white rabbits, which were randomly divided equally into high-intensity exercise and control groups. The former were forced to run for 60 min/day over 4 weeks at the speed of 30 m/min. The histological changes of cartilage and knee joint synovia were investigated with hematoxylin and eosin staining. Immunohistochemistry and enzyme-linked immunosorbent assays were performed to measure IL-15 expression.

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