Osmotic pressure

Small molecule-enrichment analysis in response to osmotic stimuli in the intervertebral disc

H. Ma, Xie, Y. Z., Zhao, J., and Ye, B., Small molecule-enrichment analysis in response to osmotic stimuli in the intervertebral disc, vol. 11, pp. 3668-3675, 2012.

The intervertebral disc (IVD) is a heterogeneous structure that contributes to load support and flexibility in the spine. IVD cells experience a broad range of physical stimuli under physiological conditions, including alterations in their osmotic environment. To date, the molecular mechanisms regulating the response of IVD to osmotic pressure are still not well understood. We obtained the gene expression profile of human IVD cells from NCBI and looked for potential therapeutic drug candidates.

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