Oral epithelial dysplasia

Screening of crucial long non-coding RNAs in oral epithelial dysplasia by serial analysis of gene expression

X. Han, Wei, Y. B., Tian, G., Tang, Z., Gao, J. Y., and Xu, X. G., Screening of crucial long non-coding RNAs in oral epithelial dysplasia by serial analysis of gene expression, vol. 14, pp. 11729-11738, 2015.

Oral epithelial dysplasia (OED) is a premalignant lesion of the oral mucosa. Considering the poor 5-year survival rate of oral cancer, further investigation is needed in order to determine the pathogenesis of OED. In the present study, serial analysis of gene expression (SAGE) data from patients with OED were compared to normal controls to identify differentially expressed genes (DEGs). SAGE data were obtained from the Gene Expression Omnibus, and included samples from patients with mild, moderate, or severe dysplasia.

Subscribe to Oral epithelial dysplasia