Northeastern Brazil

Prevalence of CCR5-Δ32 and CCR2-V64I polymorphisms in a mixed population from northeastern Brazil

H. Ferreira-Fernandes, Santos, A. C. C., Motta, F. J. N., Canalle, R., Yoshioka, F. K. N., Burbano, R. R., Rey, J. A., da Silva, B. B., and Pinto, G. R., Prevalence of CCR5-Δ32 and CCR2-V64I polymorphisms in a mixed population from northeastern Brazil, vol. 14, pp. 11710-11718, 2015.

Chemokines are low-molecular weight proteins that play a key role in inflammatory processes. Genomic variations in chemokine receptors are associated with the susceptibility to various diseases. Polymorphisms in chemokine receptor type 5 (CCR5)-Δ32 and CCR2-V64I are related to human immunodeficiency virus infection resistance, which has led to genetic association studies for several other diseases.

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