Neural precursor cell expressed developmentally downregulated 4-like

Gender flip-flop association between genetic variations of NEDD4L and metabolic syndrome in the Kazakh general population

H. M. Wang, Li, N. F., Hong, J., Zhou, L., and Chang, J. H., Gender flip-flop association between genetic variations of NEDD4L and metabolic syndrome in the Kazakh general population, vol. 13, pp. 22-31, 2014.

Genetic variation is thought to contribute to etiology of metabolic syndrome (MS). Neural precursor cell expressed developmentally downregulated 4-like gene (NEDD4L) is a candidate gene for MS. This study investigated the relationship between variations of NEDD4L and MS in the Kazakh, which is an ideal population to study the genetic mechanisms of complex diseases such as MS. We screened the promoter and exons of NEDD4L in 48 Kazakh individuals with MS to identify representative variations.

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