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Abnormal gene expression profile reveals the common key signatures associated with clear cell renal cell carcinoma: a meta-analysis

H. J. Zhang, Sun, Z. Q., Qian, W. Q., and Sheng, L., “Abnormal gene expression profile reveals the common key signatures associated with clear cell renal cell carcinoma: a meta-analysis”, vol. 14, pp. 2216-2224, 2015.

The aims of this study were to identify the common gene signatures of clear cell renal cell carcinoma (CCRCC), and to expand the respective protein-protein interaction networks associated with CCRCC regulation. For the latter, we utilized multiple gene expression data sets from the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO), with which we could analyze the aberrant gene expression patterns at the transcriptome level that distinguish cancer from normal samples.

Coordinated, network-based research as a strategic component of science in Brazil

A. J. G. Simpson, Camargo, A. A., Ferro, J. Aparecido, Parra, J., and Vasconcelos, A. Tereza, “Coordinated, network-based research as a strategic component of science in Brazil”, vol. 3, pp. 18-25, 2004.

Scientific research plays a fundamental role in the health and development of any society, since all technological advances depend ultimately on scientific discovery and the generation of wealth is intricately dependent on technological advance. Due to their importance, science and technology generally occupy important places in the hierarchical structure of developed societies, and they receive considerable public and private investment.

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