Natural killer cells

Increased CD56+ NK cells and enhanced Th1 responses in human unexplained recurrent spontaneous abortion

Y. Gao and Wang, P. L., Increased CD56+ NK cells and enhanced Th1 responses in human unexplained recurrent spontaneous abortion, vol. 14, pp. 18103-18109, 2015.

Recurrent spontaneous abortion (RSA) is reported to be associated with immune imbalance at the maternal-fetal interface. Immune cells in the decidual tissue are involved in maintaining immune tolerance during pregnancy; however, whether natural killer (NK) and T cells are altered in unexplained RSA (URSA) remains unknown. In this study, we compared the number and percentage of CD56+ NK cells, CD4+ T cells and CD8+ T cells by flow cytometry in 30 URSA patients and 30 normal pregnant controls.

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