N-methyl D-aspartate 2A

Functional polymorphisms of the glutamate receptor N-methyl D-aspartate 2A gene are associated with heroin addiction

H. J. Zhong, Huo, Z. H., Dang, J., Chen, J., Zhu, Y. S., and Liu, J. H., Functional polymorphisms of the glutamate receptor N-methyl D-aspartate 2A gene are associated with heroin addiction, vol. 13, pp. 8714-8721, 2014.

Heroin dependence is a debilitating psychiatric disorder with a complex inheritance mechanism. Genetic polymorphisms in functional regions of the glutamate receptor, N-methyl D-aspartate 2A (GRIN2A) gene, which encodes the 2A subunit of the N-methyl D-aspartate (NMDA) receptor, may modulate the risk of heroin addiction.

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