Myocardial infarction

Association between the C804A polymorphism in the TGF-β gene and the risk of myocardial infarction: a meta-analysis

D. W. Suo, Hu, Q., Chen, J., Sun, Q. H., and Guo, H., Association between the C804A polymorphism in the TGF-β gene and the risk of myocardial infarction: a meta-analysis, vol. 14, pp. 1566-1579, 2015.

Tumor necrosis factor-β (TNF-β) is an important mediator of inflammation and may play a role in the pathogenesis of myocardial infarction (MI). While several published studies have investigated the association between the C804A polymorphism in the TNF-β gene and MI risk, their results are controversial and ambiguous. In this study, we evaluated the contribution of the TNF-β C804A polymorphism to MI risk.

T174M polymorphism in the angiotensinogen gene and risk of myocardial infarction: a meta-analysis

P. Y. Hu, Wang, Y. W., Pang, X. H., and Wang, H. W., T174M polymorphism in the angiotensinogen gene and risk of myocardial infarction: a meta-analysis, vol. 14, pp. 3767-3774, 2015.

Numerous studies have evaluated the association between the T174M polymorphism in the angiotensinogen (AGT) gene and myocardial infarction (MI) risk. However, the specific association remains controversial because of small sample sizes and varied study designs among different studies. We performed a meta-analysis to assess this correlation. A comprehensive search was conducted to identify all published articles regarding the association between the AGT gene T174M polymorphism and MI risk from different databases.

Value of human brain natriuretic peptide in treatment of acute anterior myocardial infarction evaluated via three-dimensional speckle tracking imaging

Y. Zhang, Gao, F., Zhang, X. - Y., Hou, Y. - M., Tang, Y., Yang, S. - L., Zhu, S. - H., Luo, R. - Y., and Lin, S. - F., Value of human brain natriuretic peptide in treatment of acute anterior myocardial infarction evaluated via three-dimensional speckle tracking imaging, vol. 14, pp. 5699-5709, 2015.

Three-dimensional ultrasound speckle tracking imaging was used to evaluate the effects of recombinant human brain natriuretic peptide (rhBNP) in acute anterior and extensive anterior myocardial infarction. Ninety patients with acute anterior or extensive myocardial infarction were randomly divided into 3 groups: Group A [emergency percutaneous coronary intervention (PCI)], Group B (emergency PCI + rhBNP early treatment), and Group C (emergency PCI + late rhBNP treatment).

Association of genetic polymorphisms of SAA1 (rs12218) with myocardial infarction in a Chinese population

B. Y. Wang, Hang, J. Y., Zhong, Y., and Tan, S. J., Association of genetic polymorphisms of SAA1 (rs12218) with myocardial infarction in a Chinese population, vol. 13, pp. 3693-3696, 2014.

Previous studies suggested that genetic polymorphisms of serum amyloid A (SAA) were associated with carotid atherosclerosis. However, the relationship between genetic polymorphisms of SAA and myocardial infarction (MI) remains unclear. In the present study, we analyzed a polymorphism (rs12218) in the SAA1 gene in 840 MI patients and 840 healthy subjects by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method.

Association of plasma B-type natriuretic peptide concentration with myocardial infarct size in patients with acute myocardial infarction

J. M. Niu, Ma, Z. L., Xie, C., and Zhang, Z. Q., Association of plasma B-type natriuretic peptide concentration with myocardial infarct size in patients with acute myocardial infarction, vol. 13, pp. 6177-6183, 2014.

B-type natriuretic peptide (BNP) is widely used in the treatment of early-stage heart failure and coronary heart disease. In this study, the association of plasma BNP concentration with myocardial infarct (MI) size in patients with acute myocardial infarction (AMI) was investigated. Eighty patients with AMI were enrolled in the MI group and 30 healthy volunteers were selected as the control group.

An elevated plasma level of visfatin increases the risk of myocardial infarction

Y. Yang, Li, Z., Tao, H. F., Qi, X. Y., Wang, W. L., Yang, L., Wang, H., and Xu, P., An elevated plasma level of visfatin increases the risk of myocardial infarction, vol. 13, pp. 8586-8595, 2014.

Visfatin, an adipocytokine involved in metabolic and immune disorders, plays an important role in the etiology of cardiovascular disease. Recent evidence has shown that an elevated plasma level of visfatin may increase the risk of myocardial infarction (MI), but individual published studies have shown inconclusive results. This study aimed to obtain a more precise estimate of the association between the plasma visfatin level and MI risk through a detailed meta-analysis of studies published in peer-reviewed journals.

Effect of intracoronary tirofiban on platelet alpha-granule membrane protein and myocardial perfusion level during emergency percutaneous coronary intervention

H. P. Xu, Liu, C. M., and Zhang, W. W., Effect of intracoronary tirofiban on platelet alpha-granule membrane protein and myocardial perfusion level during emergency percutaneous coronary intervention, vol. 13, pp. 9599-9605, 2014.

This study aimed to investigate the effect of intracoronary application of tirofiban on platelet alpha-granule membrane protein (GMP-140) and myocardial perfusion levels during emergency percutaneous coronary intervention (PCI). A total of 70 patients who accepted emergency PCI treatment were randomly divided into tirofiban and control groups. We determined GMP-140 and troponin I (cTnI) levels before and 12 h after surgery, as well as N-terminal pro-brain natriuretic peptide levels 1 and 7 days after surgery in the two groups.

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