Association between a point mutation at the -743-bp region of the transthyretin (TTR) gene and familial vitreous amyloidosis
“Association between a point mutation at the -743-bp region of the transthyretin (TTR) gene and familial vitreous amyloidosis”, vol. 15, p. -, 2016.
, The aim of this study was to identify changes in the base sequence of the upstream regulatory region of the transthyretin (TTR) gene. Whole-blood DNA was extracted from ten subjects belonging to a family with familial amyloidosis vitreoretinopathy; the upstream regulatory sequence was amplified by polymerase chain reaction, detected by gel electrophoresis, and sequenced.