Mucinous

Expression of c-myc and mutation of the KRAS gene in patients with ovarian mucinous tumors

X. S. Li, Sun, J., and He, X. L., Expression of c-myc and mutation of the KRAS gene in patients with ovarian mucinous tumors, vol. 14, pp. 10752-10759, 2015.

We examined the expression of c-myc and mutations in the KRAS gene in ovarian mucinous tumors to explore the pathogenesis of these tumors and the feasibility of targeted gene therapy. Expression of c-myc protein and mutations in the KRAS gene in 24 cases of ovarian mucinous cystadenoma, 46 cases of ovarian borderline mucinous cystadenoma, and 46 cases of ovarian mucinous cystadenocarcinoma were detected using the immunohistochemistry PV-9000 2-step method and polymerase chain reaction-restriction fragment length polymorphism.

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