MSTN gene

Bioinformatic analysis based on the complete coding region of the MSTN gene within and among different species

X. C. Song, Xu, C., Yue, Z. G., Wang, L., Wang, G. W., Yang, F. H., Song, X. C., Xu, C., Yue, Z. G., Wang, L., Wang, G. W., Yang, F. H., Song, X. C., Xu, C., Yue, Z. G., Wang, L., Wang, G. W., and Yang, F. H., “Bioinformatic analysis based on the complete coding region of the MSTN gene within and among different species”, vol. 15, p. -, 2016.

Myostatin, encoded by the MSTN gene (previously GDF8), is a member of the transforming growth factor-β superfamily, which normally acts to limit skeletal muscle mass by regulating the number and growth of muscle fibers. In this study, a total of 84 myostatin gene sequences with known complete coding regions (CDS) and corresponding amino acid sequences were analyzed from 17 species, and differentiation within and among species was studied using comparative genomics and bioinformatics. Characteristics of the nucleotide and amino acid sequences were also predicted.

Rabbit MSTN gene polymorphisms and genetic effect analysis

X. B. Qiao, Xu, K. Y., Li, B., Luan, X., Xia, T., and Fan, X. Z., “Rabbit MSTN gene polymorphisms and genetic effect analysis”, vol. 13, pp. 2590-2597, 2014.

We analyzed meat samples of nine pure lines of rabbit and its 37 hybrid combinations by sequencing and single-strand conformation polymorphism techniques to explore genetic polymorphisms of all the three exon regions and part of the 5'-regulatory region of the myostatin (MSTN) gene. Thus, we detected a single nucleotide mutation (T→C) on the 476 locus of the 5'-regulatory region, but no mutation sites were detected in the exon areas.

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