Monocyte chemoattractant protein 1

Relationship between genetic polymorphisms in MCP-1, CCR-2, and non-small-cell lung cancer in the Han nationality of Northern China

L. Yang, Wang, J., Li, F. - G., Han, M., Chang, X. - J., and Wang, Z. - T., Relationship between genetic polymorphisms in MCP-1, CCR-2, and non-small-cell lung cancer in the Han nationality of Northern China, vol. 14, pp. 3745-3752, 2015.

Lung cancer is a common malignant tumor worldwide and is now the leading cause of cancer-related deaths. Monocyte chemoattractant protein 1 (MCP-1) and its receptor chemokine receptor 2 (CCR-2) are important chemokines. We examined the polymorphisms of 338 unrelated patients with non-small cell lung carcinoma (NSCLC) and 200 unrelated healthy controls of Han nationality in Northern China using polymerase chain reaction-restriction fragment length polymorphism.

MCP-1 gene polymorphisms in North Chinese patients with pulmonary tuberculosis

G. L. Shi, Yang, L., Sun, Y., Yin, Y. J., and Song, C. X., MCP-1 gene polymorphisms in North Chinese patients with pulmonary tuberculosis, vol. 14, pp. 4035-4040, 2015.

Pulmonary tuberculosis (PTB) remains one of the most important infectious diseases worldwide. Several studies have suggested that genetic factors may affect the susceptibility to PTB, but the specific genes involved have not been fully characterized. The gene for monocyte chemoattractant protein 1 (MCP-1) has been linked to an increased risk of tuberculosis in some Mexican and Korean populations.

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