Mongolians

Association of a CYP4A11 polymorphism and hypertension in the Mongolian and Han populations of China

J. Q. Liang, Yan, M. R., Yang, L., Suyila, Q., Cui, H. W., and Su, X. L., Association of a CYP4A11 polymorphism and hypertension in the Mongolian and Han populations of China, vol. 13, pp. 508-517, 2014.

Human cytochrome P450 4A11 (CYP4A11) plays a role in the regulation of blood pressure through the conversion of arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE). We therefore investigated the association between a CYP4A11 polymorphism (rs9333025) with hypertension in the Mongolian and Han ethnic groups. We studied 514 Mongolians in a pastoral area, including 201 hypertension patients and 313 normotensive controls, and 524 Han individuals in an urban area, including 215 hypertension patients and 309 normotensive controls.

Risk factors for the development of essential hypertension in a Mongolian population of China: a case-control study

N. Dalai, Cui, H., Yan, M., Rile, G., Li, S., and Su, X., Risk factors for the development of essential hypertension in a Mongolian population of China: a case-control study, vol. 13, pp. 3283-3291, 2014.

Lifestyle, habits, diet, and genetics are all important factors associated with the prevalence of hypertension. Many association studies have been performed in the Chinese Han population, whereas data explaining the high prevalence of hypertension in the Mongolian population remain scarce. In the present study, we aimed to determine the factors associated with the development of essential hypertension in Mongolians. A total of 194 hypertensive cases and 201 controls from Dongwu County were enrolled in the study.

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