MMP-9

MMP-9 genetic polymorphism may confer susceptibility to COPD

S. Jiang, Yang, Z. H., Chen, Y. Y., He, Z., Zhou, Y., Gao, Y., Zhang, Q., Tan, M. Q., Jiang, S., Yang, Z. H., Chen, Y. Y., He, Z., Zhou, Y., Gao, Y., Zhang, Q., Tan, M. Q., Jiang, S., Yang, Z. H., Chen, Y. Y., He, Z., Zhou, Y., Gao, Y., Zhang, Q., and Tan, M. Q., “MMP-9 genetic polymorphism may confer susceptibility to COPD”, vol. 15, p. -, 2016.

Correlations between genetic polymorphisms of three matrix metalloproteinase (MMP) genes and susceptibility to chronic obstructive pulmonary disease (COPD) were investigated. Relevant case-control studies were selected using rigorous inclusion and exclusion criteria. The comprehensive Meta-analysis 2.0 software was used to conduct the statistical analysis. An odds ratio with 95% confidence intervals was applied to assess the correlation between genetic polymorphisms of MMPs and susceptibility to COPD. Twelve high-quality studies were selected for inclusion in this meta-analysis.

High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis

G. Q. Zeng, Chen, A. B., Li, W., Song, J. H., and Gao, C. Y., “High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis”, vol. 14, pp. 14811-14822, 2015.

Our study examined the relationship between the expression of matrix metalloproteinases (MMP)-1, MMP-2, and MMP-9 proteins and the pathogenesis of osteoarthritis (OA). We employed rigorous inclusion and exclusion criteria in computer-based bibliographic databases to extract published studies relevant to this investigation. The STATA 12.0 software was used for the statistical analyses. A total of 1408 studies were initially searched, and 10 studies with 458 OA patients and 295 healthy controls were included in this meta-analysis.

Expression characteristics of MMP-2 and MMP-9 in guinea pig ovaries during the estrous cycle

J. R. Li and Shen, T., “Expression characteristics of MMP-2 and MMP-9 in guinea pig ovaries during the estrous cycle”, vol. 14, pp. 17329-17340, 2015.

We investigated the expression characteristics of matrix metalloproteinases (MMP)-2 and MMP-9 in the ovaries of normal adult guinea pigs during the estrous cycle. The estrous cycle was classified according to the appearance of the vaginal orifice and by vaginal exfoliated cell smears. Guinea pigs that had experienced at least two normal estrous cycles were selected. Ovaries were collected from guinea pigs at proestrus or metestrus (N = 6).

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