miRNA

A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer

X. Huang, Yang, Y., Cui, Z. W., Wang, J., Gao, L. B., Huang, X., Yang, Y., Cui, Z. W., Wang, J., and Gao, L. B., A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer, vol. 15, p. -, 2016.

The insertion/deletion polymorphism (rs3783553 TTCA/-) in the 3' untranslated region of interleukin-1A (IL1A) has been studied intensively and has been shown to affect tumor risk. We studied the frequency of the IL1A gene polymorphism rs3783553 and evaluated its relationship with breast cancer (BC). A hospital-based case-control study comprising 228 patients with histologically confirmed BC and 241 healthy subjects was conducted. Polymerase chain reaction was used to detect the IL1A rs3783553 polymorphism.

Identification of conserved microRNAs in peripheral blood from giant panda: expression of mammary gland-related microRNAs during late pregnancy and early lactation

C. D. Wang, Long, K., Jin, L., Huang, S., Li, D. H., Ma, X. P., Wei, M., Gu, Y., Ma, J. D., and Zhang, H., Identification of conserved microRNAs in peripheral blood from giant panda: expression of mammary gland-related microRNAs during late pregnancy and early lactation, vol. 14, pp. 14216-14228, 2015.

The giant panda (Ailuropoda melanoleuca) is one of the world’s most endangered mammals, and it has evolved several unusual biological and behavioral traits. During puberty, pregnancy, lactation, and involution, the mammary gland undergoes profound morphological and functional changes. A large number of microRNAs (miRNAs) have been identified to be involved in mammary gland development and lactation.

Differential expression of microRNAs may regulate pollen development in Brassica oleracea

J. H. Song, Yang, J., Pan, F., and Jin, B., Differential expression of microRNAs may regulate pollen development in Brassica oleracea, vol. 14, pp. 15024-15034, 2015.

MicroRNAs (miRNAs) are a class of non-coding endogenous negative regulators that regulate gene expression at both the transcriptional and post-transcriptional levels. However, little is known about the expression characteristics of miRNAs during pollen development in Brassica oleracea. In this study, five known and three novel miRNAs were identified and their expression patterns were compared in the flower buds of B. oleracea using stem-loop reverse transcription polymerase chain reaction (RT-PCR) and quantitative real-time PCR.

microRNAs in avian influenza virus H9N2-infected and non-infected chicken embryo fibroblasts

X. Peng, Gao, Q. S., Zhou, L., Chen, Z. H., Lu, S., Huang, H. J., Zhan, C. Y., and Xiang, M., microRNAs in avian influenza virus H9N2-infected and non-infected chicken embryo fibroblasts, vol. 14, pp. 9081-9091, 2015.

There is limited information about microRNAs (miR­NAs) in H9N2 subtype influenza virus-infected chicken cells or tissues. In this study, 10,487,469 and 13,119,795 reads were obtained from in­fected and non-infected chicken embryo fibroblasts, respectively. Seven hundred and thirty-six and 1004 miRNAs, including mature miRNAs and precursors, were obtained from the infected and non-infected fibro­blasts, respectively.

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