miR-21

Characterization and effects of miR-21 expression in esophageal cancer

S. - W. Wen, Zhang, Y. - F., Li1, Y., Liu, Z. - X., Lv, H. - L., Li, Z. - H., Xu, Y. - Z., Zhu, Y. - G., and Tian, Z. - Q., Characterization and effects of miR-21 expression in esophageal cancer, vol. 14, pp. 8810-8818, 2015.

The aim of this study was to investigate the expression of miR-21 in esophageal cancer and the impact of miR-21 on apoptosis, invasion, and the expression of target genes in esophageal cancer cells. Fluorescence quantitative polymerase chain reaction analysis was used to detect the expression of miR-21 in human esophageal tissues, adjacent tissues, and an esophageal cancer cell line (TE-13). The antisense miR-21 oligonucleotide was generated commercially using the solid-phase chemical synthesis method.

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