miR-149C>T

Role of miR-149C>T polymorphisms on the risk of hepatocellular carcinoma in a Chinese population

M. F. Liu, Chen, W. Q., He, Y. Z., and Gu, Y. L., Role of miR-149C>T polymorphisms on the risk of hepatocellular carcinoma in a Chinese population, vol. 13, pp. 7184-7189, 2014.

MicroRNAs (miRNAs) are thought to play a role in cancer development. We conducted a case-control study to investigate the association between polymorphisms in miR-149C>T and hepatocellular carcinoma (HCC) risk. Duplex polymerase chain reaction with the confronting 2-pair primers were taken to genotype miR-149C>T. The association between genotype frequencies of miR-149C>T and risk of HCC was estimated as odds ratios (ORs) and 95% confidence intervals (95%CIs) using conditional regression analysis.

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