MicroRNA-98

Expression of miR-98 in myocarditis and its influence on transcription of the FAS/FASL gene pair

B. Y. Zhang, Zhao, Z., Jin, Z., Zhang, B. Y., Zhao, Z., and Jin, Z., Expression of miR-98 in myocarditis and its influence on transcription of the FAS/FASL gene pair, vol. 15, p. -, 2016.

Myocarditis is a common cardiovascular disease and frequently occurs in children and teenagers. It is believed to be caused by both endogenous and exogenous factors, among which FAS/FASL gene pair-induced cell apoptosis is a major mechanism of myocardial cell injury. A previous study has detected low expression of microRNA (miR)-98 in myocarditis patients. Therefore, in this study we investigated the functional implications of miR-98 with respect to the disease. We carried out a case-control study including 50 myocarditis patients and 50 healthy individuals.

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