Expression of miR-98 in myocarditis and its influence on transcription of the FAS/FASL gene pair
“Expression of miR-98 in myocarditis and its influence on transcription of the FAS/FASL gene pair”, vol. 15, p. -, 2016.,
Myocarditis is a common cardiovascular disease and frequently occurs in children and teenagers. It is believed to be caused by both endogenous and exogenous factors, among which FAS/FASL gene pair-induced cell apoptosis is a major mechanism of myocardial cell injury. A previous study has detected low expression of microRNA (miR)-98 in myocarditis patients. Therefore, in this study we investigated the functional implications of miR-98 with respect to the disease. We carried out a case-control study including 50 myocarditis patients and 50 healthy individuals.