microRNA-301a

Upregulated microRNA-301a in osteosarcoma promotes tumor progression by targeting CDC14A

Z. Ni, Shang, X. F., Wang, Y. F., Sun, Y. J., Fu, D. J., Ni, Z., Shang, X. F., Wang, Y. F., Sun, Y. J., and Fu, D. J., Upregulated microRNA-301a in osteosarcoma promotes tumor progression by targeting CDC14A, vol. 15, p. -, 2016.

MicroRNAs (miRs) are associated with tumor progression in various cancers, such as gastric and hepatic carcinomas, and lung cancer. miR-301a is overexpressed and displays oncogenic activity in cancers. We investigated the biological involvement of miR-301a in osteosarcoma (OS). Quantitative real-time polymerase chain reaction (qRT-PCR) was used to analyze expression levels of miR-301a in 24 OS and matched adjacent non-tumor tissues. A miR-301a mimic was transferred into OS cell lines U-2 OS and MG-63 to upregulate miR-301a.

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