MicroRNA

Characterization of microRNAs and their target genes associated with transcriptomic changes in gamma-irradiated Arabidopsis

J. H. Kim, Go, Y. S., Kim, J. K., Chung, B. Y., Kim, J. H., Go, Y. S., Kim, J. K., and Chung, B. Y., Characterization of microRNAs and their target genes associated with transcriptomic changes in gamma-irradiated Arabidopsis, vol. 15, p. -, 2016.

MicroRNAs (miRNAs) regulate gene expression in response to biotic and abiotic stress in plants. We investigated gamma-ray-responsive miRNAs in Arabidopsis wild-type and cmt3-11t mutant plants using miRNA microarray analysis. miRNA expression was differentiated between the wild-type and cmt3-11t mutants. miR164a, miR169d, miR169h, miR172b*, and miR403 were identified as repressible in the wild-type and/or cmt3-11t mutant in response to gamma irradiation, while miR827, miR840, and miR850 were strongly inducible.

MicroRNA analysis in model species based on evolutionary rates

X. F. Mao, Cao, Y. C., Mao, X. F., Cao, Y. C., Mao, X. F., and Cao, Y. C., MicroRNA analysis in model species based on evolutionary rates, vol. 15, p. -, 2016.

MicroRNAs (miRNAs) are major post-transcriptional regulators of gene expression. In an attempt to gain insights into miRNAs at the macroevolutionary level, we performed a systematic analysis of miRNAs in six model organisms based on their evolutionary rates. First, we calculated their miRNA evolutionary rates, and found that they did not correlate with the complexity of the organisms.

miRQuest: integration of tools on a Web server for microRNA research

R. R. Aguiar, Ambrosio, L. A., Sepúlveda-Hermosilla, G., Maracaja-Coutinho, V., Paschoal, A. R., Aguiar, R. R., Ambrosio, L. A., Sepúlveda-Hermosilla, G., Maracaja-Coutinho, V., Paschoal, A. R., Aguiar, R. R., Ambrosio, L. A., Sepúlveda-Hermosilla, G., Maracaja-Coutinho, V., and Paschoal, A. R., miRQuest: integration of tools on a Web server for microRNA research, vol. 15, p. -, 2016.

This report describes the miRQuest - a novel middleware available in a Web server that allows the end user to do the miRNA research in a user-friendly way. It is known that there are many prediction tools for microRNA (miRNA) identification that use different programming languages and methods to realize this task. It is difficult to understand each tool and apply it to diverse datasets and organisms available for miRNA analysis. miRQuest can easily be used by biologists and researchers with limited experience with bioinformatics.

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