Mexicans

XRCC1 polymorphisms and haplotypes in Mexican patients with acute lymphoblastic leukemia

J. P. Meza-Espinoza, Peralta-Leal, V., Gutierrez-Angulo, M., Macias-Gomez, N., Ayala-Madrigal, M. L., Barros-Nuñez, P., Duran-Gonzalez, J., and Leal-Ugarte, E., XRCC1 polymorphisms and haplotypes in Mexican patients with acute lymphoblastic leukemia, vol. 8, pp. 1451-1458, 2009.

We examined the influence of the Arg194Trp, Arg280His, and Arg399Gln polymorphisms of XRCC1 (X-ray repair cross-complementing group 1) on the development of childhood acute lymphoblastic leukemia (ALL) in 120 ALL patients and 120 controls in Mexico. All of them were genotyped for these polymorphisms, using polymerase chain reaction. No significant differences in allele and genotype frequencies for any polymorphism were observed between patients and controls.

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