Mexican Mestizo population

Interethnic variation of the MMP-9 microsatellite in Amerindian and Mexican Mestizo populations: considerations for genetic association studies

R. Camacho-Mejorado, Noris, G., Santana, C., Magaña, J. J., Majluf-Cruz, A., Arellano-Galindo, J., De la Peña, A., Hernández-Juárez, J., Calderón-Aranda, E. S., Meraz-Ríos, M. A., and Gómez, R., Interethnic variation of the MMP-9 microsatellite in Amerindian and Mexican Mestizo populations: considerations for genetic association studies, vol. 14, pp. 2929-2939, 2015.

We studied the interethnic variation of the MMP-9 microsatellite in the Mestizo and Amerindian populations using blood samples collected from 435 healthy unrelated individuals from the Central Valley of Mexico. DNA samples were genotyped using the -90 (CA)12-27 repeat near the MMP transcriptional start site using capillary electrophoresis. Our data were compared with those from African, Asian, and European populations (N = 729). Both Mestizo and Amerindian populations were in Hardy-Weinberg equilibrium (P ≥ 0.05).

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