Mexican children

Mutations in NPHS2 (podocin) in Mexican children with nephrotic syndrome who respond to standard steroid treatment

J. S. Carrasco-Miranda, Garcia-Alvarez, R., Sotelo-Mundo, R. R., Valenzuela, O., Islas-Osuna, M. A., and Sotelo-Cruz, N., Mutations in NPHS2 (podocin) in Mexican children with nephrotic syndrome who respond to standard steroid treatment, vol. 12. pp. 2102-2107, 2013.

Human nephrotic syndrome has been related to mutations in glomerular proteins. Mutations in the NPHS2 gene that encodes podocin have been described as responsible for steroid-resistant nephrotic syndrome. It has been advised to test for NPHS2 mutations in parallel or before giving steroid treatment in nephrotic syndrome patients in order to avoid unnecessary therapy. We identified NPHS2 mutations in Mexican children with nephrotic syndrome.

Subscribe to Mexican children