Metastasis

Expression levels of survivin, Bcl-2, and KAI1 proteins in cervical cancer and their correlation with metastasis

X. L. Zhou and Wang, M., Expression levels of survivin, Bcl-2, and KAI1 proteins in cervical cancer and their correlation with metastasis, vol. 14, pp. 17059-17067, 2015.

Cervical cancer is associated with abnormal expression of multiple genes. Survivin and Bcl-2 proteins are apoptosis inhibitors. The tumor suppressor gene CD82, which encodes the protein KAI1, is downregulated in cervical cancer, and is associated with differentiation degree. We investigated the expression levels of three proteins and their correlation with metastasis in cervical cancer by comparing them in different cervical lesions.

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