Metallothionein

Low metallothionein 1M expression association with poor hepatocellular carcinoma prognosis after curative resection

J. Ding, Lu, S. C., Ding, J., and Lu, S. C., Low metallothionein 1M expression association with poor hepatocellular carcinoma prognosis after curative resection, vol. 15, p. -, 2016.

According to the typical clinical characteristics of hepatocellular carcinoma (HCC), recurrence and prognosis can differ dramatically between patients. Using RNA sequencing, we identified differential expression of the gene metallothionein 1M (MT1M) by comparing early-recurrence HCC (N = 11), no-recurrence HCC (N = 10), and normal liver tissues (N = 5). Reverse transcription-polymerase chain reaction was employed to test MT1M expression levels in 92 HCC tissue samples from a cohort of patients with whom contact was established for post-operative follow-up.

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