Meta-analysis

Association between 1p13.3 genomic markers and coronary artery disease: a meta-analysis involving patients and controls

J. Guo, Luo, Y. X., Tao, L. X., and Guo, X. H., Association between 1p13.3 genomic markers and coronary artery disease: a meta-analysis involving patients and controls, vol. 14, pp. 9092-9102, 2015.

Recently, genome-wide association studies on cardio­vascular disease identified a series of associated single nucleotide polymorphisms in an intergenic region of chromosome 1p13.3. We in­vestigated the association of this locus with cardiovascular disease in 13 case-control studies and undertook a meta-analysis for effect size, heterogeneity, publication bias, and strength of evidence. English and Chinese language articles were screened for the association of 1p13.3 single nucleotide polymorphisms with coronary heart/artery disease or myocardial infarction as primary outcomes.

Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis

J. Z. Peng, Xue, L., Liu, D. G., and Lin, Y. H., Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis, vol. 14, pp. 9024-9033, 2015.

Although many epidemiologic studies have investigated the p53 codon 72 polymorphism and its association with esophageal cancer (EC) in China, definite conclusions could not be drawn. To clarify the effects of p53 codon 72 polymorphism on the risk of EC, we performed a meta-analysis on the Chinese population. A total of 13 studies including 3308 patients and 5115 controls were involved in this meta-analysis.

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