Association of LRP5 Ala1330Val polymorphism with fracture risk: a meta-analysis
Numerous studies have evaluated the association between the Ala1330Val polymorphism of the low-density lipoprotein receptor-related proteins 5 (LRP5) gene and fracture risk. However, the specific association is still controversial. The aim of this study was to investigate their correlation via meta-analysis. and EMBASE databases were searched, and data were extracted independently by two reviewers. Odds ratios (ORs) with corresponding 95% confidence intervals (CIs) were used to assess the strength of the associations.