Meta-analysis

Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study and a meta-analysis

W. G. Hu, Pan, R. J., Cai, W., Wang, Z. T., and Zhu, Z. G., Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study and a meta-analysis, vol. 14, pp. 14670-14679, 2015.

The association between the human 8-oxoguanine glycosylase 1 (hOGG1) gene Ser326Cys polymorphism (rs1052133) and gastric cancer has been widely evaluated, yet a definitive answer to whether this association exists is lacking. We first conducted a case-control study to assess this association in a large Han Chinese population, and then performed a meta-analysis to further address this issue. This case-control study involved 448 patients clinically diagnosed with gastric cancer and 372 cancer-free control individuals from China.

Vascular endothelial growth factor gene polymorphisms and psoriasis susceptibility: a meta-analysis

Y. H. Lee and Song, G. G., Vascular endothelial growth factor gene polymorphisms and psoriasis susceptibility: a meta-analysis, vol. 14, pp. 14396-14405, 2015.

The aim of this study was to explore whether vascular endothelial growth factor (VEGF) polymorphisms confer susceptibil­ity to psoriasis. Meta-analyses were conducted to examine the asso­ciations between the +405 C/G, -460 C/T, -1154 A/G, and -2578 A/C polymorphisms of VEGF and psoriasis using allele contrast and reces­sive, dominant, and additive models. Seven studies on VEGF polymor­phisms and psoriasis involving 1956 subjects (psoriasis patients 665, controls 1291) were included in this meta-analysis.

Subscribe to Meta-analysis