In vitro effects and mechanisms of lycopene in MCF-7 human breast cancer cells.
“In vitro effects and mechanisms of lycopene in MCF-7 human breast cancer cells.”, Genet Mol Res, vol. 16, no. 2, 2017.
, The objective of this study was to evaluate the estrogenic effects and mechanisms of three flavonoid components in Xiaoyao powder: quercetin, kaempferol, and isorhamnetin. The drugs were used to treat estrogen receptor (ER)-positive human breast cancer MCF-7 cells, and proliferation was measured using the MTT method. The expression of proteins and mRNA of the ER subtype were measured using western blotting and real time polymerase chain reaction.