mBMMSCs

EZH2 suppresses hepatocellular differentiation of mouse bone marrow mesenchymal stem cells

T. Lu, Sun, H., Lv, J., Yang, M. F., Zhang, F., Qian, Y., and Dong, X. J., EZH2 suppresses hepatocellular differentiation of mouse bone marrow mesenchymal stem cells, vol. 13, pp. 2231-2239, 2014.

Our previous studies have indicated that mouse bone marrow mesenchymal stem cells (mBMMSCs) have potential to differentiate into hepatocytes with high efficiency. Our study aimed to evaluate the role of the mouse histone methyltransferase enhancer of zeste homolog 2 gene (EZH2) in the hepatocellular differentiation of mBMMSCs. The mBMMSCs isolated from femurs and tibias were cultured in Iscove's modified Eagle's medium (IMEM) supplemented with 10% fetal bovine serum.

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