Matrix metalloproteinase-9

Association between matrix metalloproteinase-9 rs3918242 polymorphism and development of coronary artery disease in a Chinese population

L. M. Qin, Qin, G. M., Shi, X. H., Wang, A. L., Zuo, H., Qin, L. M., Qin, G. M., Shi, X. H., Wang, A. L., and Zuo, H., Association between matrix metalloproteinase-9 rs3918242 polymorphism and development of coronary artery disease in a Chinese population, vol. 15, p. -, 2016.

We conducted a case-control study to investigate the role of one single nucleotide polymorphism of MMP-9 rs3918242 in the development of coronary artery disease. The rs3918242 was amplified with 435-bp DNA fragments using polymerase chain reaction coupled with restriction fragment length polymorphism.

Role of PPARα in down-regulating AGE-induced TGF-β and MMP-9 expressions in chondrocytes

J. Wang, Wang, G., Sun, G. W., Wang, J., Wang, G., and Sun, G. W., Role of PPARα in down-regulating AGE-induced TGF-β and MMP-9 expressions in chondrocytes, vol. 15, p. -, 2016.

Peroxisome proliferator-activated receptor is closely associated with the pathogenesis of osteoarthritis. The level of exogenous advanced glycation end-products (AGEs) in articular cartilage is highly associated with the severity of osteoarthritic lesions. However, their interactions and role in promoting osteoarthritisprogression remain unclear.

Association study between matrix metalloproteinase-9 gene (MMP9) polymorphisms and the risk of Henoch-Schönlein purpura in children

E. D. Xu, Xiao, Y. F., Wang, J. J., Dong, L., Xu, E. D., Xiao, Y. F., Wang, J. J., and Dong, L., Association study between matrix metalloproteinase-9 gene (MMP9) polymorphisms and the risk of Henoch-Schönlein purpura in children, vol. 15, p. -, 2016.

Henoch-Schönlein purpura nephritis (HSPN), the most serious long-term complication of Henoch-Schönlein purpura, is one of the most common renal diseases in children. Matrix metalloproteinase-9 (MMP-9) is implicated in the pathogenesis of renal diseases. Genomic DNA was isolated from the venous blood leukocytes of 220 unrelated patients with HSPN and 205 unrelated healthy individuals.

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