Malondialdehyde

Neuroprotective effect of ketamine on acute spinal cord injury in rats

S. H. Tang, Yu, J. G., Li, J. J., and Sun, J. Y., “Neuroprotective effect of ketamine on acute spinal cord injury in rats”, vol. 14, pp. 3551-3556, 2015.

The aim of this study was to investigate the neuroprotective effects of ketamine during acute spinal cord injury in rats. Sprague Dawley (SD) rats (N = 70) were randomly divided into three groups: sham-operated (N = 10), control (N = 30), and treatment (N = 30) groups. The moderate spinal cord injury model was established. After injury, the sham-operated group received no drug, the treatment group received intraperitoneal ketamine injections, and the control group received intraperitoneal normal saline injections.

Malondialdehyde and SOD-induced changes of gastric tissues in acute gastric mucosal injury under positive acceleration

J. Li, Tang, H. L., Chen, Y., Fan, Q., Shao, Y. T., Jia, M., Wang, J. C., and Yang, C. M., “Malondialdehyde and SOD-induced changes of gastric tissues in acute gastric mucosal injury under positive acceleration”, vol. 14, pp. 4361-4368, 2015.

The aim of this study was to investigate the impacts of positive acceleration (+Gz) on the gastric mucosal tissues in cases of acute gastric mucosal injury and to explore the role of oxygen free radicals. Thirty Sprague Dawley rats were randomly divided into the absolute ethanol control group (A group), absolute ethanol +5Gz group (B group), absolute ethanol +10Gz group (C group). Following centrifugation, the gastric tissues of each group were studied for the presence of gastric mucosal injuries and morphological changes.

Protective effects of remifentanil preconditioning on cerebral injury during pump-assisted coronary artery bypass graft

T. Z. Zhang, Zhou, J., Jin, Q., Sun, Y. J., Diao, Y. G., Zhang, Y. N., and Zhang, Z., “Protective effects of remifentanil preconditioning on cerebral injury during pump-assisted coronary artery bypass graft”, vol. 13, pp. 7658-7665, 2014.

The protective effects of remifentanil preconditioning on serum superoxide dismutase (SOD) and malondialdehyde (MDA) during pump-assisted coronary artery bypass graft (CABG) were investigated. Forty pump-assisted CABG patients were randomly divided into a remifentanil preconditioning group (R group) and a control group (C group, N = 10; normal saline). The R group was further divided into 3 sub-groups (R1, R2, and R3; N = 10 per group) according to the remifentanil dose (0.6, 1.2, and 1.8 μg·kg-1·min-1, respectively).

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