Macrophage

Xiayuxue decoction reduces renal injury by promoting macrophage apoptosis in hepatic cirrhotic rats

C. Liu, Cai, J., Cheng, Z., Dai, X., Tao, L., Zhang, J., and Xue, D., Xiayuxue decoction reduces renal injury by promoting macrophage apoptosis in hepatic cirrhotic rats, vol. 14, pp. 10760-10773, 2015.

Renal pathological changes in cirrhotic rat have not been extensively reported. The aim of this study was to investigate whether Xiayuxue decoction (XYXD) could attenuate renal injury induced by bile duct ligation (BDL), with special focus on the mechanisms promoting renal macrophage apoptosis. The rats were treated with BDL for 5 weeks and administered 0.36 g/kg XYXD intragastrically from day 1 of initiating BDL. Renal tissue was monitored by hematoxylin-eosin and Sirius red staining.

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