Lymphatic metastasis

Effects of forkhead box C2 on carcinogenesis and lymphatic metastasis in endometrial carcinoma

Y. Y. Fan, Deng, W. G., Liu, Y. N., Li, Y. Y., Deng, S. L., and Fu, Y., Effects of forkhead box C2 on carcinogenesis and lymphatic metastasis in endometrial carcinoma, vol. 14, pp. 5535-5547, 2015.

We investigated the distribution of endometrial lymphatic vessels and expression of forkhead box C2 (FOXC2) in normal endometrium during menstrual cycle and in endometrial adenocarcinoma. Full-thickness uterine samples and endometrial adenocarcinoma samples were collected for immunohistochemical analysis using D2-40 and FOXC2 mouse monoclonal antibodies. The lymphatic vessel density (LVD) of the endometrium was significantly reduced compared with the myometrium during the cycle.

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