LPS

Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens

B. Deng, Yu, T., Liu, W., Ye, S. Q., Wang, L. X., Yang, Y., Gong, P., Ran, Z. P., Huang, H. J., and Wen, J. H., Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens, vol. 14, pp. 17312-17321, 2015.

Lipopolysaccharide (LPS), the major component of the outer cell wall of Gram-negative bacteria, activates the immune system and threatens the health of livestock and poultry. However, little is known about the genes and pathways involved in the immune response of ducklings to LPS. To elucidate the genes involved in the response of 7-day-old duckling spleens treated with LPS, RNA from LPS-treated and control duckling spleens was analyzed by RNA-Seq. The results showed 11,095 and 10,840 genes with >10 clean reads in the LPS-treated and control groups, respectively.

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