Liver cirrhosis

Study on the effects of blueberry treatment on histone acetylation modification of CCl-induced liver disease in rats.

W. Zhan, Liao, X., Tian, T., Yu, L., Liu, X., Li, B., Liu, J., Han, B., Xie, R. J., Ji, Q. H., and Yang, Q., “Study on the effects of blueberry treatment on histone acetylation modification of CCl-induced liver disease in rats.”, Genet Mol Res, vol. 16, no. 1, 2017.

IL10 rs1800896 polymorphism is associated with liver cirrhosis and chronic hepatitis B

L. N. Cao, Cheng, S. L., Liu, W., Cao, L. N., Cheng, S. L., and Liu, W., “IL10 rs1800896 polymorphism is associated with liver cirrhosis and chronic hepatitis B”, vol. 15, p. -, 2016.

We conducted a case-control study to assess the role of two IL10 gene polymorphisms (rs1800896 and rs1800872) in susceptibility to liver cirrhosis, and their association with chronic hepatitis B in a Chinese population. A case-control study was designed to investigate the association between functional polymorphisms of IL10 (rs1800896 and rs1800872) and the development of liver cirrhosis. Between March 2012 and March 2014, we recruited 241 patients with liver cirrhosis and 254 controls from Xianyang Central Hospital.

Xiayuxue decoction reduces renal injury by promoting macrophage apoptosis in hepatic cirrhotic rats

C. Liu, Cai, J., Cheng, Z., Dai, X., Tao, L., Zhang, J., and Xue, D., “Xiayuxue decoction reduces renal injury by promoting macrophage apoptosis in hepatic cirrhotic rats”, vol. 14, pp. 10760-10773, 2015.

Renal pathological changes in cirrhotic rat have not been extensively reported. The aim of this study was to investigate whether Xiayuxue decoction (XYXD) could attenuate renal injury induced by bile duct ligation (BDL), with special focus on the mechanisms promoting renal macrophage apoptosis. The rats were treated with BDL for 5 weeks and administered 0.36 g/kg XYXD intragastrically from day 1 of initiating BDL. Renal tissue was monitored by hematoxylin-eosin and Sirius red staining.

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